The idea here is to get a close up of a person (newscaster style) with a picture (or video) floating next to them.
(1) On seperate video tracks, put two pictures in Vegas. Notice in the video preview that one is covering the other.
(2) Click the Event Pan/Crop on the top video clip.....errr picture in this case.
(3) Use sizing handles.
(4) Final product should look bout like this.